蛋白創製研究部｜論文発表

2011年　

InoueI, Zheng B, Watanabe K, Ishikawa Y, Shiba K, Yasueda H, Uraoka Y, Yamashita I
A novel bifunctional protein supramolecule for construction of carbon nanotube-titanium hybrid material.
Chem Comm 47(47): 12649-12651 (2011)

Matsumura S, Aoki I, Saga T, Shiba K
A tumor-environment-responsive nanocarrier that evolves its surface properties upon sensing matrix metalloproteinase-2 and initiates agglomeration to enhance T2 relaxivity for magnetic resonance imaging
Mol Pharm 8(5): 1970-1974 (2011)

Murakami T, Kashiwagi K, Shiba K
Creation of novel signalling modulators from existing cytokine using scanning motif-programming
Chem Comm 47(33): 9357-9359 (2011)

Kasai T, Matsumura S, Iizuka T, Shiba K, Kanamori T, Yudasaka M, Iijima S, Yokoyama A
Carbon nanohorns accelerate bone regeneration in rat calvarial bone defect
Nanotechnol 22: 065102 (8pp) (2011)

Tsuji T, Onuma K, Yamamoto A, Iijima M, Shiba K
Physicochemical properties of artificial proteins that accelerate nucleation of crystalline calcium phosphate
J Cryst Growth 314: 190–195 (2011)

2010年　

Tsuji T, Oaki Y, Yoshinari M, Kato T, Shiba K
Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on the titanium substrates
Chem Comm 46(36): 6675-6677 (2010)

Ikemi M, Kikuchi T, Matsumura S, Shiba K, Sato S, Fujita M
Peptide-coated, self-assembled M₁₂L₂₄ coordination spheres and their immobilization onto an inorganic surface
Chem Sci 1 : 68-71 (2010)

Sano K, Minamisawa T, Shiba K
Autonomous silica encapsulation and sustained release of anticancer protein
Langmuir 26(4) : 2231-2234 (2010)

総説・解説など

佐野健一、芝清隆
バイオミネラリゼーション研究の新展開ーミネラルの形成と溶解を制御するー
バイオサイエンスとインダストリー 68(5): 336-340(2010)

Shiba K
Exploitation of peptide motif sequences and their use in nanobiotechnology
Curr Opin Biotechnol 21: 412–425 (2010)

Shiba K
Natural and artificial peptide motifs: their origins and the application of motif-programming
Chem Soc Rev 39(1): 117-126 (2010)

2009年　

Hayashi T, Sano K, Shiba K, Iwahori K, Yamashita I, Hara M
Critical amino acid residues for the specific binding of the Ti-recognizing recombinant ferritin with oxide surfaces of titanium and silicon
Langmuir 25(18): 10901-10906 (2009)

Patwardhan P, Shiba K, Gordon C, Craddock BP, Minamisawa T, Miller WT
Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs
ACS Chem Biol 4(9): 751-758 (2009)

Yoshinari M, Kato T, Matsuzaka K, Hayakawa T, Shiba K
Prevention of biofilm formation on titanium surfaces modified with conjugated molecules comprised of antimicrobial and titanium-binding peptides
Biofouling 26(1): 103-110 (2009)

Matsukawa N, Nishio K, Sano K, Shiba K, Yamashita I
Hexagonal close-packed array formed by selective adsorption onto hexagonal patterns
Langmuir 25(6): 3327–3330 (2009)

Miyawaki J, Matsumura S, Yuge R, Murakami T, Sato S, Tomida A, Tsuruo T, Ichihashi T, Fujinami T, Irie H, Tsuchida K, Iijima S, Shiba K, Yudasaka M
Biodistribution and ultrastructural localization of single-walled carbon nanohorns determined in vivo with embedded Gd₂O₃ labels
ACS Nano 3(6): 1399-1406 (2009)

Chirila TV, Minamisawa T, Keen I, Shiba K
Effect of motif-programmed artificial proteins on the calcium uptake in a synthetic hydrogel
Macromol Biosci 9(10): 959-967 (2009)

Matsumura S, Sato S, Yudasaka M, Tomida A, Tsuruo T, Iijima S, Shiba K
Prevention of carbon nanohorn agglomeration using a conjugate composed of comb-shaped polyethylene glycol and a peptide aptamer
Molecular Pharmaceutics 6(2): 441-447 (2009)

Kashiwagi K, Tsuji T, Shiba K
Directional BMP-2 for functionalization of titanium surfaces
Biomaterials 30(6): 1166-1175 (2009)

総説・解説など

芝清隆
モチーフ・プログラムド人工タンパク質の医療分野での応用
YAKUGAKU ZASSHI 129(11): 1295-1303 (2009)

柏木健司、芝清隆
階層的進化を模した人工タンパク質の創製
超分子サイエンス＆テクノロジー　基礎からイノベーションまで国武豊喜（監修）エヌティーエス, 1000-1008 (2009)

芝清隆
がん治療におけるペプチド・アプタマーとナノキャリアの役割
癌と化学療法 36(3): 362-365 (2009)

芝清隆
モチーフをユニットとした人工分子の創製
実践ゲノムの最前線　井村裕夫（監修）　六然社 : 146-148 (2009)